{"id":2996,"date":"2025-04-10T16:39:10","date_gmt":"2025-04-10T14:39:10","guid":{"rendered":"https:\/\/formulazdravlja.com\/?p=2996"},"modified":"2025-04-10T16:41:34","modified_gmt":"2025-04-10T14:41:34","slug":"kako-omega-3-vitamin-d-i-vezbanje-usporavaju-biolosko-starenje-nova-otkrica-iz-do-health-studije","status":"publish","type":"post","link":"https:\/\/formulazdravlja.com\/en\/kako-omega-3-vitamin-d-i-vezbanje-usporavaju-biolosko-starenje-nova-otkrica-iz-do-health-studije\/","title":{"rendered":"How Omega-3, Vitamin D, and Exercise Slow Down Biological Aging: New Findings from the DO-HEALTH Study"},"content":{"rendered":"<p>Recent research suggests that dietary supplements such as omega-3 fatty acids and vitamin D, along with regular exercise, may have a significant impact on slowing the process of biological aging in older adults. A study published in Nature Aging offers new insights into these potential benefits.<\/p>\n\n\n\n<p><strong>What Is Biological Aging?<\/strong><\/p>\n\n\n\n<p>Biological aging refers to cellular and tissue changes that occur over time, increasing the risk of various diseases. Unlike chronological aging, which simply measures the number of years lived, biological aging can vary among individuals of the same age.<\/p>\n\n\n\n<p><strong>Study Highlights<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>As part of the DO-HEALTH clinical trial, researchers monitored 777 healthy participants over the age of 70 for a period of three years.<\/li>\n\n\n\n<li>The aim was to examine the effects of daily supplementation with 2,000 IU of vitamin D, 1 gram of omega-3 fatty acids, and a simple home-based exercise program on biological aging markers, specifically epigenetic markers based on DNA methylation.<\/li>\n\n\n\n<li>The markers analyzed included:<br>DNA methylation age (the so-called epigenetic clock), reflecting biological rather than chronological aging;<br>DNAm PAI-1 (Plasminogen Activator Inhibitor-1) \u2013 an epigenetic marker linked to inflammation, metabolic imbalance, and aging;<br>DNAm leptin \u2013 an epigenetic indicator of leptin hormone activity, involved in appetite regulation, metabolism, and body weight;<br>Methylation patterns associated with mortality and chronic disease risk, used to predict long-term health outcomes.<\/li>\n<\/ul>\n\n\n\n<p><strong>Key Results<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Omega-3 Fatty Acids:<\/strong> Participants who received omega-3 supplements showed a slower biological aging rate, with an average reduction of 2.9 to 3.8 months over three years.<\/li>\n\n\n\n<li><strong>Combination Therapy:<\/strong> The combination of omega-3, vitamin D, and exercise provided additional benefits, especially on specific biological aging markers.<\/li>\n<\/ul>\n\n\n\n<p><strong>Conclusion<\/strong><\/p>\n\n\n\n<p>These findings suggest that omega-3 fatty acids\u2014especially when combined with vitamin D and regular physical activity\u2014may offer protective effects against biological aging in older adults. Although the effects were modest, they point to promising strategies for promoting healthy aging.<\/p>\n\n\n\n<p>For more information, the full article is available in <a href=\"https:\/\/www.nature.com\/articles\/s43587-024-00793-y\">Nature Aging<\/a>.\u00a0 <\/p>\n\n\n\n<p>That\u2019s why <a href=\"https:\/\/formulazdravlja.com\/en\/prokol-formula-zdravlja\/\">The HEALTH FORMULA protocol<\/a> combines the latest scientific evidence with practical and easy-to-apply recommendations that can support vitality, immunity, and healthy aging.<\/p>\n\n\n\n<p>Based on individual needs, this protocol offers personalized guidance for:<br>\ud83d\udd39 Optimal doses of omega-3 fatty acids and vitamin D,<br>\ud83d\udd39 A customized physical activity plan,<br>\ud83d\udd39 And other proactive strategies that support a long, healthy life.<\/p>\n\n\n\n<p>Health is built day by day \u2013 start early!<\/p>","protected":false},"excerpt":{"rendered":"<p>Nedavna istra\u017eivanja su pokazala da dodaci ishrani poput omega-3 masnih kiselina, vitamina D, kao i redovno ve\u017ebanje, mogu imati zna\u010dajan uticaj na usporavanje procesa biolo\u0161kog starenja kod starijih osoba. Studija objavljena u \u010dasopisu Nature Aging pru\u017ea uvid u ove potencijalne benefite. \u0160ta je Biolo\u0161ko Starenje? Biolo\u0161ko starenje odnosi se na promene u \u0107elijama i tkivima [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2998,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2996","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/posts\/2996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/comments?post=2996"}],"version-history":[{"count":4,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/posts\/2996\/revisions"}],"predecessor-version":[{"id":3001,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/posts\/2996\/revisions\/3001"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/media\/2998"}],"wp:attachment":[{"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/media?parent=2996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/categories?post=2996"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/formulazdravlja.com\/en\/wp-json\/wp\/v2\/tags?post=2996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}