Xylitol: Sweetener Linked to Higher Risk of Heart Attack and Stroke**

In recent years, xylitol has become a popular low-calorie sweetener, often found in reduced-sugar products, chewing gum, and toothpaste. However, a new study published in the European Heart Journal points to potential health risks associated with its use.

Study Results

A research team in the US and Europe tracked over 3,000 participants for three years. They discovered that individuals with the highest levels of xylitol in their plasma were significantly more likely to experience heart attacks, strokes, or even death. The researchers also studied the immediate effects of xylitol by examining platelet activity in volunteers who consumed a xylitol-sweetened drink compared to those who drank a glucose-sweetened beverage. The results showed a dramatic 1000-fold increase in xylitol levels following the xylitol-sweetened drink.

What is Xylitol?

Xylitol is a sugar alcohol naturally found in small amounts in fruits and vegetables. Its use as a sugar substitute has surged in the last decade, leading to its presence in various processed foods and dental hygiene products. Despite its benefits in reducing sugar intake, these recent findings suggest that high levels of xylitol consumption could pose serious cardiovascular risks.

Expert Opinions

Dr. Stanley Hazen, chair of the Department of Cardiovascular and Metabolic Sciences at Cleveland Clinic's Lerner Research Institute, emphasized that "this study again shows the immediate need for investigating sugar alcohols and artificial sweeteners, especially as they continue to be recommended in combating conditions like obesity or diabetes." He also advised caution, stating, "It does not mean throw out your toothpaste if it has xylitol in it, but we should be aware that consumption of a product containing high levels could increase the risk of blood clot-related events."

Industry Response

In response to the study, the Calorie Control Council, representing the low- and reduced-calorie food and beverage industry, noted that xylitol has been approved for decades by government agencies. They argued that the study results might not apply to the general population, highlighting that some participants already had a higher predisposition for cardiovascular issues.

Conclusion

While xylitol offers a low-calorie alternative to sugar, this study underscores the importance of understanding the potential health implications of its use. As the debate continues, it is crucial for consumers to stay informed and consider moderation when using sugar substitutes.

Sources:
- European Heart Journal: "Xylitol is prothrombotic and associated with cardiovascular risk."
- Cleveland Clinic: "Cleveland Clinic-Led Study Links Sugar Substitute to Increased Risk of Heart Attack and Stroke."
- Calorie Control Council: "CCC Statement in Response to Xylitol is Prothrombotic and Associated with Cardiovascular Risk."